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CAS No.:12122-67-7

Name: zineb

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human LDLo oral 5gm/kg (5000mg/kg)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A420, Pg. 1984,
mammal (species unspecified) LD50 unreported 1350mg/kg (1350mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(5), Pg. 29, 1980.
mouse LD50 intraperitoneal 1940mg/kg (1940mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 121, 1982.
mouse LD50 oral 7600mg/kg (7600mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: ATAXIA
Journal of Toxicology and Environmental Health. Vol. 4, Pg. 93, 1978.
 
rabbit LD50 oral 4450mg/kg (4450mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 121, 1982.
rat LCLo inhalation 800mg/m3/4H (800mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 121, 1982.
rat LD50 oral 1850mg/kg (1850mg/kg) BEHAVIORAL: EXCITEMENT
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 31(10), Pg. 25, 1966.
rat LD50 skin > 2500mg/kg (2500mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.
rat LD50 unreported 1850mg/kg (1850mg/kg)   Environmental Quality and Safety, Supplement. Vol. 3, Pg. 618, 1975.


Consensus Reports:

 


SAFETY PROFILE:

Hazard Codes: Xi 
Risk Statements: 37-43
R37: Irritating to the respiratory system 
R43: May cause sensitization by skin contact
Safety Statements:  8-24/25-46
S8: Keep container dry
S24: Avoid contact with skin 
S25: Avoid contact with eyes
S46: If swallowed, seek medical advice immediately and show this container or label.  


Standards and Recommendations:

 


Analytical Methods:

 


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