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Current position:Home > Products > ()-17-CYCLOPROPYLMETHYLMORPHINAN-3,4-DIOL

CAS No.:42281-59-4

Name: ()-17-CYCLOPROPYLMETHYLMORPHINAN-3,4-DIOL

Details Introduction

TOXICITY DATA with REFERENCEļ¼š

1.   

orl-hmn TDLo:14 µg/kg:CNS,GIT,KID

    JCPCBR    Journal of Clinical Pharmacology. 16 (4)(1976),183.
2.   

scu-hmn TDLo:26 µg/kg:CNS

    DRFUD4    Drugs of the Future. 2 (1977),746.
3.   

scu-mus LD50:315 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 193 (1975),23.
4.   

ivn-mus LD50:32 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 193 (1975),23.

SAFETY PROFILEļ¼š
Poison by subcutaneous and intravenous routes. Human systemic effects by ingestion and subcutaneous routes: somnolence, tremors, ataxia (loss of muscle coordination), hypermotility, diarrhea, and changes in the kidney, ureter, or bladder. When heated to decomposition it emits toxic fumes of NOx.

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