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Current position:Home > Products > 1,1-Dimethylhydrazine hydrochloride

CAS No.:593-82-8

Name: 1,1-Dimethylhydrazine hydrochloride

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 96mg/kg (96mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
mouse LD50 intraperitoneal 466mg/kg (466mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: REGIDITY
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
mouse LD50 intravenous 402mg/kg (402mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: REGIDITY

BEHAVIORAL: EXCITEMENT
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
mouse LD50 oral 426mg/kg (426mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: REGIDITY
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
rat LD50 intraperitoneal 210mg/kg (210mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
rat LD50 intravenous 191mg/kg (191mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
rat LD50 oral 196mg/kg (196mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.


Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Risk Statements 20/21-28
R20/21:Harmful by inhalation and in contact with skin. 
R28:Very toxic if swallowed.
Safety Statements 22-36/37/39-45
S22:Do not breathe dust. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 2811
RTECS MV2900000


Standards and Recommendations:

NIOSH REL: (Hydrazines) CL 0.15 mg/m3/2H


Analytical Methods:

 


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