CAS No.:593-82-8
Name: 1,1-Dimethylhydrazine hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intravenous | 96mg/kg (96mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956. |
mouse | LD50 | intraperitoneal | 466mg/kg (466mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: EXCITEMENT BEHAVIORAL: REGIDITY |
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956. |
mouse | LD50 | intravenous | 402mg/kg (402mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: REGIDITY BEHAVIORAL: EXCITEMENT |
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956. |
mouse | LD50 | oral | 426mg/kg (426mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: EXCITEMENT BEHAVIORAL: REGIDITY |
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956. |
rat | LD50 | intraperitoneal | 210mg/kg (210mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956. |
rat | LD50 | intravenous | 191mg/kg (191mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956. |
rat | LD50 | oral | 196mg/kg (196mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Risk Statements 20/21-28
R20/21:Harmful by inhalation and in contact with skin.
R28:Very toxic if swallowed.
Safety Statements 22-36/37/39-45
S22:Do not breathe dust.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 2811
RTECS MV2900000
Standards and Recommendations:
NIOSH REL: (Hydrazines) CL 0.15 mg/m3/2H
Analytical Methods:
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