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Current position:Home > Products > 1,2-Dimethylhydrazine

CAS No.:540-73-8

Name: 1,2-Dimethylhydrazine

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

otr-hmn:fbr 230 µmol/L

    CALEDQ    Cancer Letters (Shannon, Ireland). 29 (1985),265.
2.    

dns-hmn:lng 100 µL/L

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD-A041-973 .
3.    

sce-mus-rec 20 mg/kg

    ENMUDM    Environmental Mutagenesis. 8 (Suppl 6)(1986),41.
4.    

hma-mus/esc 50 µmol/kg

    MUREAV    Mutation Research. 148 (1985),1.
5.    

dnd-ham:lng 2 mmol/L

    MUREAV    Mutation Research. 173 (1986),157.
6.    

sce-mus-ipr 270 µmol/kg

    TCMUD8    Teratogenesis, Carcinogenesis, and Mutagenesis. 9 (1989),219.
7.    

orl-rat LD50:100 mg/kg

    NATWAY    Naturwissenschaften. 54 (1967),285.
8.    

ihl-rat LCLo:280 ppm/4H

    AMIHAB    AMA Archives of Industrial Health. 12 (1955),609.
9.    

ipr-rat LD50:163 mg/kg

    MEPAAX    Medycyna Pracy. Industrial Medicine. 24 (1973),71.
10.    

scu-rat LD50:220 mg/kg

    XENOBH    Xenobiotica. 3 (1973),271.
11.  

Consensus Reports:

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 4 ,1974,p. 145.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.


SAFETY PROFILE:

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and intramuscular routes. Moderately toxic by inhalation. Human mutation data reported. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. A high-energy propellant for liquid-fueled rockets. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: ToxicT,DangerousN
Risk Statements: 45-23/24/25-51/53 
R45: May cause cancer. 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed. 
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 53-45-61 
S53: Avoid exposure - obtain special instructions before use. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 2382
HazardClass: 6.1(a)
PackingGroup: I


Standards and Recommendations:

DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
DOT Classification:  3; Label: Flammable Liquid, Poison


Analytical Methods:

 


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