CAS No.:540-73-8
Name: 1,2-Dimethylhydrazine
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
otr-hmn:fbr 230 µmol/L |
CALEDQ Cancer Letters (Shannon, Ireland). 29 (1985),265. | ||
2. |
dns-hmn:lng 100 µL/L |
NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD-A041-973 . | ||
3. |
sce-mus-rec 20 mg/kg |
ENMUDM Environmental Mutagenesis. 8 (Suppl 6)(1986),41. | ||
4. |
hma-mus/esc 50 µmol/kg |
MUREAV Mutation Research. 148 (1985),1. | ||
5. |
dnd-ham:lng 2 mmol/L |
MUREAV Mutation Research. 173 (1986),157. | ||
6. |
sce-mus-ipr 270 µmol/kg |
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. 9 (1989),219. | ||
7. |
orl-rat LD50:100 mg/kg |
NATWAY Naturwissenschaften. 54 (1967),285. | ||
8. |
ihl-rat LCLo:280 ppm/4H |
AMIHAB AMA Archives of Industrial Health. 12 (1955),609. | ||
9. |
ipr-rat LD50:163 mg/kg |
MEPAAX Medycyna Pracy. Industrial Medicine. 24 (1973),71. | ||
10. |
scu-rat LD50:220 mg/kg |
XENOBH Xenobiotica. 3 (1973),271. | ||
11. |
Consensus Reports:
IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 4 ,1974,p. 145.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
SAFETY PROFILE:
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and intramuscular routes. Moderately toxic by inhalation. Human mutation data reported. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. A high-energy propellant for liquid-fueled rockets. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: T,N
Risk Statements: 45-23/24/25-51/53
R45: May cause cancer.
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 53-45-61
S53: Avoid exposure - obtain special instructions before use.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 2382
HazardClass: 6.1(a)
PackingGroup: I
Standards and Recommendations:
DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
DOT Classification: 3; Label: Flammable Liquid, Poison
Analytical Methods:
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