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CAS No.:40762-15-0
Name: 1,3-DIHYDRO-7-CHLORO-5-(o-FLUORO-PHENYL)-3-HYDROXY-1-(2-HYDROXY-ETHYL)-2H-1,4-BENZODIAZEPIN-2-ONE
Details Introduction
TOXICITY DATA with REFERENCEļ¼
| 1. | unr-hmn TDLo:71 µg/kg:CNS | DRFUD4 Drugs of the Future. 3 (1978),145. | ||
| 2. | orl-rat LD50:2550 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1294. | ||
| 3. | ipr-rat LD50:586 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1294. | ||
| 4. | ipr-mus LD50:760 mg/kg | JPPMAB Journal of Pharmacy and Pharmacology. 26 (1974),566. |
SAFETY PROFILEļ¼
Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by an unspecified route: somnolence. When heated to decomposition it emits very toxic fumes of Cl−, F−, and NOx.
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