CAS No.:39603-53-7
Name: 1-(NITROSOPROPYLAMINO)-2-PROPANOL
Details Introduction
TOXICITY DATA with REFERENCE:
1. | mma-sat 500 nmol/plate | ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 86 (1976),293. | ||
2. | scu-ham TDLo:100 mg/kg/(14D preg):NEO,TER | ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 90 (1977),119. | ||
3. | scu-rat LD50:1273 mg/kg | JNCIAM Journal of the National Cancer Institute. 54 (1975),937. | ||
4. | scu-mus LD50:1235 mg/kg | ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 91 (1978),189. | ||
5. | scu-ham LD50:1500 mg/kg | JNCIAM Journal of the National Cancer Institute. 52 (1974),1245. |
Consensus Reports:IARC Cancer Review: Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE:
Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by subcutaneous route. An experimental teratogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
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