CAS No.:103-85-5

TOXICITY DATA with REFERENCE：

 1-Phenyl-2-thiourea (103-85-5) is classified as extremely toxic. The probable oral lethal dose is 5-50 mg/kg or between 7 drops and 1 teaspoon for a 70 kg (150 lb.) person.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	25mg/kg (25mg/kg)		National Technical Information Service. Vol. AD277-689,
mouse	LD50	oral	10mg/kg (10mg/kg)		Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,
rabbit	LD50	oral	40mg/kg (40mg/kg)		Journal of Medicinal and Pharmaceutical Chemistry. Vol. 4, Pg. 109, 1961.
rat	LD50	intraperitoneal	5mg/kg (5mg/kg)	ENDOCRINE: HYPERGLYCEMIA	Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 186, 1947.
rat	LD50	oral	3mg/kg (3mg/kg)		Journal of Medicinal and Pharmaceutical Chemistry. Vol. 4, Pg. 109, 1961.

Consensus Reports：

NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-148 ,1978. . EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Dangerous disaster hazard; emits toxic fumes of oxides of sulfur and nitrogen when heated to decomposition. Avoid acids or acid fumes.
Safety Information of  1-Phenyl-2-thiourea (103-85-5):
Hazard Codes: T+
Risk Statements: 28-43
28:  Very Toxic if swallowed
43:  May cause sensitization by skin contact
Safety Statements: 28-36/37-45
28:  After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Standards and Recommendations：

 

Analytical Methods：