CAS No.:33100-27-5
Name: 15-Crown-5
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 514mg/kg (514mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
mouse | LD50 | oral | 1020mg/kg (1020mg/kg) | BEHAVIORAL: TREMOR | Toxicology and Applied Pharmacology. Vol. 44, Pg. 263, 1978. |
rabbit | LD50 | intraperitoneal | 560mg/kg (560mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(2), Pg. 48, 1987. | |
rabbit | LD50 | skin | 2520mg/kg (2520mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
rat | LD50 | intraperitoneal | 530mg/kg (530mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
rat | LD50 | oral | 1410mg/kg (1410mg/kg) | BEHAVIORAL: TREMOR | Drug and Chemical Toxicology. Vol. 1, Pg. 339, 1978. |
Consensus Reports:
Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Moderately toxic by ingestion, skin contact, and intraperitoneal routes. A skin and eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:Xn, Xi
Risk Statements: 22-36/38-36-20/22-36/37/38-20/21/22
R22: Harmful if swallowed.
R36/38: Irritating to eyes and skin.
R36: Irritating to eyes.
R20/22: Harmful by inhalation and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-39-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39: Wear eye / face protection.
S36: Wear suitable protective clothing.
RIDADR: 2810
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 6.1(b)
PackingGroup of 15-Crown-5 (CAS NO.33100-27-5): III
Standards and Recommendations:
Analytical Methods:
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