CAS No.:21436-97-5
Name: 2,4,5-Trimethylaniline Hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE:
Toxicity information about 2,4,5-Trimethylaniline Hydrochloride (CAS NO.21436-97-5) is:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 340mg/kg (340mg/kg) | Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institut by Bio-Research Consultants, Inc. Vol. NCI-E-68-1311, Pg. 1973, | |
rat | LD50 | oral | 1585mg/kg (1585mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 167, Pg. 223, 1969. |
Consensus Reports:
IARC Cancer Review: Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 ,1982,p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE:
Poison by intraperitoneal route. Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Standards and Recommendations:
Analytical Methods:
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