CAS No.:110-65-6

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	75mg/kg (75mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
guinea pig	LD50	oral	130mg/kg (130mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: OTHER CHANGES	Hygiene and Sanitation Vol. 33(1-3), Pg. 41, 1968.
mouse	LCLo	inhalation	150mg/m3/2H (150mg/m3)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI BLOOD: HEMORRHAGE	Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 13, 1965.
mouse	LD50	oral	105mg/kg (105mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: OTHER CHANGES	Hygiene and Sanitation Vol. 33(1-3), Pg. 41, 1968.
rabbit	LD50	oral	150mg/kg (150mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: OTHER CHANGES	Hygiene and Sanitation Vol. 33(1-3), Pg. 41, 1968.
rat	LCLo	inhalation	150mg/m3/2H (150mg/m3)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI BLOOD: HEMORRHAGE	Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 13, 1965.
rat	LD50	intraperitoneal	52435ug/kg (52.435mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 26, Pg. 597, 1974.
rat	LD50	oral	105mg/kg (105mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: OTHER CHANGES	Hygiene and Sanitation Vol. 33(1-3), Pg. 41, 1968.

Consensus Reports：

 

SAFETY PROFILE：

A poison by ingestion. A skin sensitizer upon long or repeated contact. Moderately explosive. When heated to decomposition it emits acrid smoke and fumes and may explode. Explosive reaction with traces of alkalies, alkali earth hydroxides, halide salts, strong acids, mercury salts + strong acids. See also ACETYLENE COMPOUNDS and ALKYNES.
Heating with strongly alkaline materials should be avoided.
Butynediol(110-65-6) is corrosive and irritates the skin and eyes. 
Hazard Codes: T,C
Risk Statements: 21-23/25-34-43-48/22 
R21:Harmful in contact with skin. 
R23/25:Toxic by inhalation and if swallowed. 
R34:Causes burns. 
R43:May cause sensitization by skin contact. 
R48/22:Harmful: danger of serious damage to health by prolonged exposure if swallowed.
Safety Statements: 25-26-36/37/39-45-46 
S25:Avoid contact with eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S46:If swallowed, seek medical advice immediately and show this container or label.
RIDADR: UN 2716 6.1/PG 3
WGK Germany: 2
RTECS: ES0525000
F: 23-10
HazardClass: 6.1
PackingGroup: III
HS Code: 29053980

Standards and Recommendations：

 

Analytical Methods：