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Current position:Home > Products > 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine

CAS No.:60560-33-0

Name: 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 177mg/kg (177mg/kg)   New Cardiovascular Drugs. Vol. 3, Pg. 133, 1985.
mouse LD50 oral 412mg/kg (412mg/kg)   New Cardiovascular Drugs. Vol. 3, Pg. 133, 1985.
rat LD50 intravenous 155mg/kg (155mg/kg)   New Cardiovascular Drugs. Vol. 3, Pg. 133, 1985.
rat LD50 oral 210mg/kg (210mg/kg)   New Cardiovascular Drugs. Vol. 3, Pg. 133, 1985.
rat LD50 subcutaneous 7070mg/kg (7070mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

BLOOD: HEMORRHAGE

BLOOD: CHANGES IN SPLEEN
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19, Pg. 2473, 1991.


Consensus Reports:

Cyanide and its compounds are on the Community Right-To-Know List.


SAFETY PROFILE:

Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and CN. See also CYANIDE.
Safety Information of 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl):
Hazard Codes: Xn
Risk Statements:  22-36/37/38
22:  Harmful if swallowed 
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
Safety Statements: 36
36:  Wear suitable protective clothing


Standards and Recommendations:

 


Analytical Methods:

 


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