CAS No.:60560-33-0
Name: 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intravenous | 177mg/kg (177mg/kg) | New Cardiovascular Drugs. Vol. 3, Pg. 133, 1985. | |
mouse | LD50 | oral | 412mg/kg (412mg/kg) | New Cardiovascular Drugs. Vol. 3, Pg. 133, 1985. | |
rat | LD50 | intravenous | 155mg/kg (155mg/kg) | New Cardiovascular Drugs. Vol. 3, Pg. 133, 1985. | |
rat | LD50 | oral | 210mg/kg (210mg/kg) | New Cardiovascular Drugs. Vol. 3, Pg. 133, 1985. | |
rat | LD50 | subcutaneous | 7070mg/kg (7070mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA BLOOD: HEMORRHAGE BLOOD: CHANGES IN SPLEEN |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19, Pg. 2473, 1991. |
Consensus Reports:
Cyanide and its compounds are on the Community Right-To-Know List.
SAFETY PROFILE:
Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and CN−. See also CYANIDE.
Safety Information of 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl):
Hazard Codes: Xn
Risk Statements: 22-36/37/38
22: Harmful if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements: 36
36: Wear suitable protective clothing
Standards and Recommendations:
Analytical Methods:
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