CAS No.:99464-64-9
Name: Ampiroxicam
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
monkey | LD50 | oral | > 500mg/kg (500mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 36, Pg. 432, 1994. | |
mouse | LD50 | intraperitoneal | 1358mg/kg (1358mg/kg) | Drugs in Japan Vol. -, Pg. 119, 1995. | |
mouse | LD50 | oral | 2291mg/kg (2291mg/kg) | Drugs in Japan Vol. -, Pg. 119, 1995. | |
mouse | LD50 | subcutaneous | 4259mg/kg (4259mg/kg) | Drugs in Japan Vol. -, Pg. 119, 1995. | |
rat | LD50 | intraperitoneal | 282mg/kg (282mg/kg) | Drugs in Japan Vol. -, Pg. 119, 1995. | |
rat | LD50 | oral | 747mg/kg (747mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE KIDNEY, URETER, AND BLADDER: INCONTINENCE |
Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 1, 1992. |
rat | LD50 | subcutaneous | 2598mg/kg (2598mg/kg) | Drugs in Japan Vol. -, Pg. 119, 1995. |
Consensus Reports:
SAFETY PROFILE:
Standards and Recommendations:
Analytical Methods:
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