CAS No.:590-63-6
Name: Bethanechol
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
scu-hmn TDLo:130 mg/kg:SKN |
34ZIAG Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,130. | ||
2. |
scu-man TDLo:1071 µg/kg/3D-I:SKN |
ARDEAC Archives of Dermatology. 95 (1967),499. | ||
3. |
orl-rat LD50:1500 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
4. |
scu-rat LD50:175 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
5. |
ivn-rat LD50:21 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
6. |
ims-rat LD50:220 mg/kg |
NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),139. | ||
7. |
orl-mus LD50:250 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
8. |
scu-mus LD50:120 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
9. |
ivn-mus LD50:10 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
10. |
ims-mus LD50:192 |
Consensus Reports:
Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Poison by ingestion, subcutaneous, intramuscular and intravenous routes. Human systemic effects by subcutaneous route: allergic dermatitis and sweating. Used as a synthetic cholinergic drug. When heated to decomposition it emits very toxic fumes of NH3, NOx, and Cl−. See also CARBAMATES.
Hazard Codes:
Xn: Harmful
Risk Statements about (2-Hydroxypropyl)trimethylammonium chloride carbamate (590-63-6):
R22 Harmful if swallowed.
Safety Statements about (2-Hydroxypropyl)trimethylammonium chloride carbamate (590-63-6):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Standards and Recommendations:
Analytical Methods:
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