CAS No.:1563-66-2

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	420ug/kg (0.42mg/kg)		Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973.
bird - wild	LD50	skin	100mg/kg (100mg/kg)		Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973.
chicken	LD50	oral	6300ug/kg (6.3mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967.
dog	LC50	inhalation	52mg/m3 (52mg/m3)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING	JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970.
dog	LD50	oral	19mg/kg (19mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING	JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970.
duck	LD50	oral	415ug/kg (0.415mg/kg)		Toxicology and Applied Pharmacology. Vol. 22, Pg. 556, 1972.
guinea pig	LC50	inhalation	43mg/m3/4H (43mg/m3)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. N5182, Pg. 1967,
mammal (species unspecified)	LD50	skin	837mg/kg (837mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(2), Pg. 89, 1988.
mouse	LD50	intravenous	450ug/kg (0.45mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#11280,
mouse	LD50	oral	2mg/kg (2mg/kg)		Journal of Agricultural and Food Chemistry. Vol. 18, Pg. 793, 1970.
mouse	LD50	unreported	5mg/kg (5mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(10), Pg. 23, 1984.
pigeon	LD50	oral	1330ug/kg (1.33mg/kg)		ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail	LD50	oral	3160ug/kg (3.16mg/kg)		ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
rabbit	LD50	skin	885mg/kg (885mg/kg)		Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 81, 1973.
rabbit	LD50	unreported	885mg/kg (885mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 192, 1971.
rat	LC50	inhalation	85mg/m3 (85mg/m3)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING	JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970.
rat	LD50	oral	5mg/kg (5mg/kg)		Pesticide Science. Vol. 1, Pg. 117, 1970.
rat	LD50	skin	120mg/kg (120mg/kg)		World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat	LD50	unreported	19mg/kg (19mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(10), Pg. 23, 1984.
women	TDLo	oral	1200ug/kg (1.2mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): SWEATING: OTHER	Khigiena i Zdraveopazvane. Hygiene and Sanitation. Vol. 24, Pg. 445, 1981.

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes of Carbofuran (CAS NO.1563-66-2): T+,N,T
Risk Statements: 26/28-50/53 
R26/28: Very toxic by inhalation and if swallowed. 
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 36/37-45-60-61-1/2 
S36/37: Wear suitable protective clothing and gloves. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S60: This material and its container must be disposed of as hazardous waste. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets. 
S1/2: Keep locked up and out of the reach of children.
RIDADR: UN 2811 6.1/PG 1
WGK Germany: 3
RTECS: FB9450000
HazardClass: 6.1(a)
PackingGroup: I

Standards and Recommendations：

 

Analytical Methods：