CAS No.:6921-27-3
Name: Propargyl ether
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | oral | 913mg/kg (913mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: NAUSEA OR VOMITING LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)" |
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 19, Pg. 389, 1960. |
rabbit | LD50 | oral | 168mg/kg (168mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: FOOD INTAKE (ANIMAL) LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)" |
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 19, Pg. 389, 1960. |
rat | LD50 | oral | 539mg/kg (539mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: FOOD INTAKE (ANIMAL) LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)" |
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 19, Pg. 389, 1960. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion. Forms thermally unstable explosive peroxides in air. When heated to decomposition it emits acrid smoke and irritating fumes. See also ACETYLENE COMPOUNDS and ALKYNES and ETHERS.
Hazard CodesXn,Xi
Risk Statements 10-19-22
R10:Flammable.
R19: 2-Propynyl ether (CAS NO.6921-27-3) may form explosive peroxides.
R22:Harmful if swallowed.
Safety Statements 16-36
S16:Keep away from sources of ignition.
S36:Wear suitable protective clothing.
RIDADR UN 3271 3/PG 3
WGK Germany 3
RTECS UK5950000
Hazard Note Irritant
HazardClass 3.1
PackingGroup II
Standards and Recommendations:
Analytical Methods:
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