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Current position:Home > Products > Propargyl ether

CAS No.:6921-27-3

Name: Propargyl ether

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 913mg/kg (913mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: NAUSEA OR VOMITING
LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)"
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 19, Pg. 389, 1960.
rabbit LD50 oral 168mg/kg (168mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: FOOD INTAKE (ANIMAL)
LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)"
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 19, Pg. 389, 1960.
rat LD50 oral 539mg/kg (539mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: FOOD INTAKE (ANIMAL)
LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)"
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 19, Pg. 389, 1960.


Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion. Forms thermally unstable explosive peroxides in air. When heated to decomposition it emits acrid smoke and irritating fumes. See also ACETYLENE COMPOUNDS and ALKYNES and ETHERS.
Hazard CodesHarmfulXn,Xi
Risk Statements 10-19-22
R10:Flammable. 
R19: 2-Propynyl ether (CAS NO.6921-27-3) may form explosive peroxides. 
R22:Harmful if swallowed.
Safety Statements 16-36
S16:Keep away from sources of ignition. 
S36:Wear suitable protective clothing.
RIDADR UN 3271 3/PG 3
WGK Germany 3
RTECS UK5950000
Hazard Note Irritant
HazardClass 3.1
PackingGroup II


Standards and Recommendations:

 


Analytical Methods:

 


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