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Current position:Home > Products > 1,2,3,7,8-Pentachlorodibenzo-p-dioxin

CAS No.:40321-76-4

Name: 1,2,3,7,8-Pentachlorodibenzo-p-dioxin

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 3100ng/kg (0.0031mg/kg)   Toxicology and Applied Pharmacology. Vol. 44, Pg. 335, 1978.
mouse LD50 oral 337500ng/kg (0.3375mg/kg)   Toxicology and Applied Pharmacology. Vol. 44, Pg. 335, 1978.
rat LD50 oral 206ug/kg (0.206mg/kg)   Archives of Toxicology. Vol. 66, Pg. 471, 1992.


Consensus Reports:

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 ,1977,p. 41.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 ,1977,p. 41.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210)


SAFETY PROFILE:

Poison by ingestion. Questionable carcinogen. When heated to decomposition it emits toxic fumes of Cl. See also CHLORINATED HYDROCARBONS, AROMATIC.
RIDADR 2811
HazardClass 6.1(a)
PackingGroup I


Standards and Recommendations:

 


Analytical Methods:

 


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