CAS No.:40321-76-4
Name: 1,2,3,7,8-Pentachlorodibenzo-p-dioxin
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | oral | 3100ng/kg (0.0031mg/kg) | Toxicology and Applied Pharmacology. Vol. 44, Pg. 335, 1978. | |
mouse | LD50 | oral | 337500ng/kg (0.3375mg/kg) | Toxicology and Applied Pharmacology. Vol. 44, Pg. 335, 1978. | |
rat | LD50 | oral | 206ug/kg (0.206mg/kg) | Archives of Toxicology. Vol. 66, Pg. 471, 1992. |
Consensus Reports:
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 ,1977,p. 41.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 ,1977,p. 41.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210)
SAFETY PROFILE:
Poison by ingestion. Questionable carcinogen. When heated to decomposition it emits toxic fumes of Cl−. See also CHLORINATED HYDROCARBONS, AROMATIC.
RIDADR 2811
HazardClass 6.1(a)
PackingGroup I
Standards and Recommendations:
Analytical Methods:
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