CAS No.:58484-07-4
Name: 1-(2-CHLOROETHYL)-3-(-d-GLUCOPYRANOS-YL)-1-NITROSOUREA
Details Introduction
TOXICITY DATA with REFERENCEļ¼
| 1. | dnd-mus:leu 100 µmol/L | INSSDM INSERM Symposium. 19 (1981),49. | ||
| 2. | dni-mus/leu 10 mg/kg | CNREA8 Cancer Research. 37 (1977),783. | ||
| 3. | ivn-rat LD50:40 mg/kg | GANNA2 Gann. Japanese Journal of Cancer Research. 68 (1977),247. | ||
| 4. | ipr-mus LD50:15 mg/kg | CNREA8 Cancer Research. 37 (1977),783. | ||
| 5. | ipr-mus LDLo:10 mg/kg | CNREA8 Cancer Research. 37 (1977),2615. | ||
| 6. | ivn-mus LD10:10 mg/kg | ANBCB3 Antibiotics and Chemotherapy. 23 (1978),64. |
SAFETY PROFILEļ¼
Poison by intravenous and intraperitoneal routes. Many N-nitroso compounds are carcinogens. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and Cl−. See also N-NITROSO COMPOUNDS.
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