CAS No.:68-88-2
Name: Hydroxyzine
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
orl-rat LD50:840 mg/kg |
CHTPBA Chimica Therapeutica. 3 (1968),210. | ||
2. |
ipr-rat LD50:160 mg/kg |
CHTPBA Chimica Therapeutica. 3 (1968),210. | ||
3. |
ivn-rat LD50:45 mg/kg |
ANPBAZ Acta Neurologia et Psychiatrica Belgica. 61 (1961),669. | ||
4. |
orl-mus LD50:480 mg/kg AANEAB 7,87,63 |
|||
5. |
ipr-mus LD50:81,300 µg/kg |
DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. 23 (1971),281. | ||
6. |
ivn-mus LD50:137 mg/kg |
27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,237. |
Consensus Reports:
SAFETY PROFILE:
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
Attentions:
1. Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
2. Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Standards and Recommendations:
Analytical Methods:
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