CAS No.:60-87-7
Name: Promethazine
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
eye-rbt 100 mg SEV |
FCTOD7 Food and Chemical Toxicology. 20 (1982),573. | ||
2. |
eye-rbt 100 mg/4S rns MLD |
FCTOD7 Food and Chemical Toxicology. 20 (1982),573. | ||
3. |
dni-hmn:fbr 80 nmol/L |
DNSYAG Diseases of the Nervous System. 29 (1968),829. | ||
4. |
otr-ham:emb 10 mg/L |
ENMUDM Environmental Mutagenesis. 8 (Suppl 6)(1986),4. | ||
5. |
msc-ham:lng 10 mg/L |
SHIGAZ Shigaku. Ondotology. 70 (1983),943. | ||
6. |
skn-cld TDLo:13 mg/kg:EYE,PSY |
CMAJAX Canadian Medical Association Journal. 130 (1984),1460. | ||
7. |
ipr-rat LDLo:140 mg/kg |
TXAPA9 Toxicology and Applied Pharmacology. 1 (1959),156. | ||
8. |
scu-rat LD50:700 mg/kg |
CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. 144 (1950),887. | ||
9. |
ivn-rat LD50:45 mg/kg |
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 120 (1959),450. | ||
10. |
ims-rat LD50:169 mg/kg |
TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. | ||
11. | & |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion, intravenous, intramuscular, intraperitoneal, and subcutaneous routes. Human systemic effects by ingestion: pupillary dilation, wakefulness, hallucinations, and distorted perceptions. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. A severe eye irritant. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Standards and Recommendations:
Analytical Methods:
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