CAS No.:52049-26-0
Name: 1-(2-CHLOROETHYL)-3-(cis-4-HYDROXY CYCLOHEXYL)-1-NITROSOUREA
Details Introduction
TOXICITY DATA with REFERENCEļ¼
1. | ipr-mus LD50:60,180 µg/kg | NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 . | ||
2. | ivn-mus LD10:25 mg/kg | ANBCB3 Antibiotics and Chemotherapy. 23 (1978),64. | ||
3. | ipl-mus LDLo:33 mg/kg | JMCMAR Journal of Medicinal Chemistry. 18 (1975),634. |
SAFETY PROFILEļ¼
Poison by intravenous, implant and intraperitoneal routes. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also N-NITROSO COMPOUNDS.
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