CAS No.:56239-24-8
Name: 1-(2-Chloroethyl)-3-(trans-4-hydro-xycyclohexyl)-1-nitrosourea
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD10 | intravenous | 12mg/kg (12mg/kg) | Antibiotics and Chemotherapy Vol. 23, Pg. 64, 1978. | |
| mouse | LD50 | intraperitoneal | 52420ug/kg (52.42mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, | |
| mouse | LDLo | intrapleural | 35mg/kg (35mg/kg) | Journal of Medicinal Chemistry. Vol. 18, Pg. 634, 1975. |
Consensus Reports：
SAFETY PROFILE：
Poison by implant, intravenous and intraperitoneal routes. Human mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of NOx and Cl−. See also N-NITROSO COMPOUNDS.
Standards and Recommendations：
Analytical Methods：
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